| General Information
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Research and Trials
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Milan - Dino Ferrari ALS Clinic
- Institute of Neurology
University of Milan Medical School
IRCCS Ospedale Maggiore
Via F. Sforza 35
I-20122 Milan - Italy
- Phone: 39-2-5503-3855
- Fax: 39-2-55190392
- Email: Vincenzo.Silani@
venere.inet.it
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- Medical Director:
- Vincenzo Silani, M.D.
- Specialty:
- Neurology (neurodegenerative diseases).
- Other medical specialties:
- Muscular dystrophies, mitochondrial diseases, immune neuropathies, muscle
pathology, spinal muscular atrophies, inflammatory myopathies, MS, stroke,
extrapyramidal disorders.
- Other diseases/conditions treated:
- Immunosuppressive treatments in immune
neuropathies.
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- Research interests:
- Neuronal tissue culture, neurochemistry,
neurotransplantation, molecular genetics; neurodegenerative (ALS and
Parkinson's) and neurogenetic diseases (myotonic muscular dystrophy,
spinal muscular atrophies).
- Research emphasis:
- Basic research on rodent and human motor neurons in culture;
trophic factor effects; molecular biology of MN diseases (SMA and fALS);
lesioned animal models; immunological causes of MN diseases.
Clinical research on upper/lower motor neuron neurophysiological interactions;
motor neuron neurophysiological quantification.
- Clinical trials in progress:
- Cephalon IGF-I early open access program and open
label Riluzole early access program.
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- Contact person: Vincenzo Silani, M.D.
- Phone: 39 -2- 55033887
- Fax: 39-2-55190392
- Email: Vincenzo.Silani@venere.inet.it
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Pisa - Università degli Studi di Pisa
- Department of Neurosciences
Section of Neurology
Via Roma 67
56126 Pisa (I)
- Phone: 39-50-992443
- Fax: 39-50-554808
- Email: gsicilia@neuro.med.unipi.it
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- Medical Director:
- Luigi Murri M.D.
- Other medical specialties:
- Muscular dystrophies, mitochondrial myopathies,
MS, stroke, epilepsy, Parkinson's disease, Alzheimer's disease.
- Other diseases/conditions treated:
- MS, Parkinson's disease
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- Research emphasis:
- Genetics of muscular dystrophies; neurodegenerative
diseases (ALS, Parkinson's, Alzheimer's), mitochondrial myopathies
(endurance test, effects of aerobic training).
- Clinical trials in progress:
- Riluzole, Interferon
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- Contact person: Gabriele Siciliano, M.D., PhD.
- Phone: 39-50-993046
- Fax: 39-50-554808
- Email: gsicilia@neuro.med.unipi.it
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Palermo - ALS Clinical Research Center
- Institute of Neuropsichiatry
University of Palermo
Via G. La Loggia 1
90100 Palermo
- Phone: +39-091-6555158
- Fax: +39-091-6555198
- Email: alsgroup@yahoo.com
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- Medical Director:
- Federico Piccoli, M.D.
- Specialty:
- Neurology (neurodegenerative diseases).
- Other medical specialties:
- Spinal muscular atrophies, myopathies, muscular dystrophies, cerebrovascular diseases, Multiple Sclerosis, epilepsy, extrapyramidal disorders, Alzheimer's disease.
- Other diseases/conditions treated:
- Multiple Sclerosis, extrapyramidal disorders, epilepsy, Alzheimer's disease, cerebrovascular diseases.
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- Research interests:
- Neuronal cell cultures; neurochemistry; molecular mechanism(s) of neurodegenerative diseases; neuronal cell death; biology of neural stem cells.
- Research emphasis:
- Basic research on spinal motoneurons in culture; molecular biology of motor neuron diseases; sex hormones in ALS; phenotypic and genotypic modifiers of disease progression in ALS; biochemical functions of the SMN isoforms in SMA; excitotoxicity and neurodegenerative disorders; use of clinimetric scales to predict disease progression in ALS and other neurodegenerative disorders.
- Clinical trials in progress:
- Effect of minocycline and creatine on disease progression in ALS.
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- Contact person: Vincenzo La Bella, M.D, Ph.D.
- Phone: +39-091-6555158
- Fax: +39-091-6555198
- Email: labella@unipa.it
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- Record last reviewed:
- 04 Sep 2002
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Torino - Torino ALS Center
- II Division of Neurology, Department of Neuroscience,
University of Torino and San Giovanni Hospital
Via Cherasco, 15, I-10126
Torino, Italy
- Phone: 39-011-6335439
- Fax: 39-011-6963487
- Email: achio@usa.net
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- Medical Director of the ALS Center:
- Adriano Chiò, M.D.
- Medical Director of the Institution:
- Roberto Mutani, M.D.
- Specialty:
- Neurology (neurodegenerative diseases)
- Other medical specialties:
- Neuromuscular disorders, neuro-oncology, degenerative diseases, paraneoplastic disorders of the CNS, neuropathology (brain, nerve, muscle), ataxic disorders, epilepsy.
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- Research emphasis:
- Nutrition, models of care, respiratory support, speech therapy, epidemiology (Piemonte ALS Register), risk factors (environmental, genetic), genetics, animal models of ALS, neuropathology of ALS.
- Clinical trials in progress:
- Pharmacological: creatine, topiramate.
- Non pharmacological: early nutrition interventions, speech and swallowing therapy.
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- Contact person: Adriano Chiò, M.D.
- Phone: 39-011-6335439
- Fax: 39-011-6963487
- Email: achio@usa.net
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- Record last reviewed:
- 29 Aug 2002
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Modena - Clinica Neurologica - Ospedale Policlinico
- Università di Modena
Via del Pozzo 71
41100 Modena
- Phone: 059-422264
- Fax: 059-424299
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- Director:
- Prof. Paolo Frigio Nichelli
- Specialty:
- Neurology
- Chief for ALS assistance and research:
- Patrizia Sola, M.D., PhD, Neurologist
- Other diseases treated in our clinic:
- dementias, movement disorders, multiple sclerosis, neuropathies, myopathies.
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- Research emphasis:
- Search for herpesviruses 6 and 8 sequences in the blood, CSF and nervous tissue of ALS; epidemiology.
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- Contact person: Patrizia Sola, M.D.
- Phone: 059-422475
- Fax: 059-424299
- Email: sola.patrizia@unimo.it
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- Record last reviewed:
- 29 Aug 2002
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