ALS Research Centers - United Kingdom

General Information	Research and Trials
Newcastle MND Clinic Department of Neurology Royal Victorian Infirmary Newcastle Upon Tyne, NE 1 4LP, United Kingdom Phone: 44-191-2325131, ext. 25467 Fax: 44-191-2610881 E-mail: Pamela.Shaw@ncl.ac.uk Director: Dr. Pamela Shaw	Research emphasis: Glutamate and free radical mechanisms of motor nuerone injury. Clinical trials: In 1997, SR57746A
Royal London Hospital Neurology-Neuromuscular Clinic Royal London Hospital London E11BB, United Kingdom Phone: 44-171-377-7472 Fax: 44-207-377-7318 E-mail: mswash@btinternet.com or michael.swash@ bartsandthelondon.nhs.gov.uk Director: Professor Michael Swash, M.D. FRCP Specialty: Neurology Collaborator in European Familial ALS study group; member of the European ALS Consortium	Research emphasis: EMG analysis in ALS,as well as studies on fasciculations, and problems of measurement in clinical trials in ALS. Clinical and neurophysiological studies on measures of disease progression. Clinical Trials in progress: Sanofi Contact: Professor Michael Swash, M.D. FRCP E-mail: michael.swash@ bartsandthelondon. nhs.gov.uk Record last reviewed: 28 Jun 2002
Dundee Royal Infirmary ALS/MND Research Clinic Department of Neurology Ninewells Hospital Dundee DD1 9SY Scotland, United Kingdom Phone: 01382 660111 Fax: 01382 425739 E-mail: robert.swingler@tuht.scot.nhs.uk Director: R. J. Swingler M.D. FRCP(UK)	Research: Scottish MND register; epidemiology and genetics of MND/ALS Clinical trials: Sanofi Contact: Shuna Colville Phone: 01382 660111 ext 6654 Fax: 01382 425739 Record last reviewed: 18 Jun 2002
Oxford - MND Care Centre University Department of Clinical Neurology University of Oxford The Radcliffe Infirmary, Oxford OX2 6HE, United Kingdom Phone: 01865-229547 Fax: 01865-790493 E-mail: kevin.talbot@clneuro.ox.ac.uk Medical Director: Dr. Kevin Talbot Specialty: Neurology	Research emphasis: In vitro and in vivon models of motor neuron degeneration Imaging Neuropathology Genetics Contact: Dr. Kevin Talbot Phone: 01865-229547 Fax: 01865-790493 E-mail: kevin.talbot@clneuro.ox.ac.uk Record last reviewed: 16 May 2006
ALS Clinic - Royal Preston Hospital Department of Neurology Royal Preston Hospital Sharoe Green Lane Fulwood, Preston, PR2 9HT, United Kingdom Phone: 44-1772 522545 Fax: 44-1772-718746 E-mail: douglas.mitchell@lthtr.nhs.uk Director: Professor J. D. Mitchell, M.D., FRCP	Research emphasis: Genetic epidemiology, assessment of bulbar function, muscle strength testing, oxidative stress in sporadic MND, calcium channel antibodies and excitotoxicity. Clinical trials in progress: Xaliproden long term study Contact: Mary O'Brien, Joyce Gardham, or Robert Addison Jones Phone: 44-1772-522545 Fax: 44-1772-718746 E-mail: joyce.gardham@ lthtr.nhs.uk Record last reviewed: 29 Jul 2002
London - Charing Cross MND Care and Research Centre Charing Cross Hospital Fulham Palace Road London W6 8RF, United Kingdom *West London Neurosciences Centre* Medical director: Dr. Roberto J. Guiloff Phone: 44-208-846-1196 Fax: 44-208-746-8420 E-mail: r.guiloff@ic.ac.uk Medical specialties: Respiratory medicine, ear nose and throat, dietetics, speech therapy, gastroenterology, psychological medicine, physiotherapy, rehabilitation, communication aids, occupational therapy. Other diseases treated: Neuromuscular diseases *Department of Neuromuscular Diseases, Division of Neuroscience and Psychological Medicine, Imperial College School of Medicine.* Head of Department: Professor Jackie de Belleroche PhD DSc FRCPathol. Phone: 44-208-846-7052 Fax: 44-208-846-7099 E-mail j.belleroche@ic.ac.uk Other clinic information: Support for families with Familial Amyotrophic Lateral sclerosis / Familial Motor Neurone Disease. Information sheets Newsletter Helpline at http://www.med.ic.ac.uk/divisions/ template_divisions _departments.asp?id=56	*West London Neurosciences Centre* Research emphasis: Assessment methods, clinical trials, clinical neurophysiology, neuropathology of MND. Other research information: The centre has participated in clinical trials with a TRH analogue, first multicentre European Study on branched chain aminoacids, riluzole and myotrophin. (IgF1). The centre uses a variety of methods in the management of patients, including the Charing Cross qualitative and and quantitative assessment scales. Contact person: MND/ALS Phone: 44-208-846-1196 Fax: 44-208-746-8420 E-mail: r.guiloff@ic.ac.uk *Department of Neuromuscular Diseases* Research emphasis: Neurogenetics, biochemical pathology experimental gene delivery and other treatment approaches.
London - King's MND Care & Research Clinic Kings College Hospital Academic Neuroscience Building PO 41, Institute of Psychiatry Camberwell London, SE5 8AF, United Kingdom Phone: 020-7848-5172 Fax: 020-7848-5190 E-mail: clinic@iop.kcl.ac.uk Website: http://www.mndcentre.org.uk Medical director: Professor P.N. Leigh Other medical specialties: Familial ALS, respiratory medicine, psychological medicine,gastroenterology,speech and language therapy, physiotherapy, dietetics, occupational therapy.	Research emphasis: Molecular genetics; molecular cell biology; functional imaging; respiratory physiology and assisted ventilation; clinical trials; emotional and psychological aspects of MND. Clinical trials in progress: We have recruited 36 patients into the trial of SR57746A (Protocol EFC 1923: Riluzole + SR57746A versus Riluzole + placebo). We will start a trial of intrathecal human recombinant BDNF (Amgen) towards the end of 1998. Contact: Emma Willey, Nurse Co-ordinator Phone: 020-7848-5172 Fax: 020 7848 5190 E-mail: clinic@iop.kcl.ac.uk Record last reviewed: 16 May 2006
London - Royal Free Hospital Department of Neurology Royal Free Hospital Pond Street London NW3 2QG United Kingdom Phone: 020-7830-2387 Fax: 020-7431-1577 E-mail: r.orrell@rfc.ucl.ac.uk Director: Richard W. Orrell, BSc M.D. FRCP Speciality: Neurology, neuromuscular diseases, neurogenetics. Other conditions treated: All neuromuscular disorders and diseases.	Research emphasis: Cause and treatment of motor neuron diseases/ALS. Familial motor neuron disease/ALS, clinical and molecular biology, assessment and advice. Contact person: Dr. Richard W Orrell, Senior Lecturer and Consultant Neurologist Department of Neurology Royal Free Hospital Pond Street London NW3 2QG England Phone: 020 7830 2387 Fax: 020-7431-1577 Email r.orrell@medsch.ucl.ac.uk Record last reviewed: 19 Dec 2006
Liverpool - Liverpool MND Care and Research Centre The Walton Centre for Neurology and Neurosurgery NHS Trust Lower Lane, Fazakerley Liverpool L9 7LJ United Kingdom Phone: 44-151-529-5711 Fax: 44-151-529-5512 E-mail: young-c@wcnn-tr.nwest.nhs.uk Website: http://www.thewaltoncentre.co.uk Medical Director: Dr. Carolyn Young	Research emphasis: Quality of life issues, scale development (dyspnoea, social withdrawal, coping strategies), attitudes towards life sustaining therapies. Contact person: James Lee, Service Co-ordinator Phone: 44-151-529-5070 Fax: 44-151-529-2477 E-mail: mnd.coordinator@ wcnn-tr.nwest.nhs.uk Record last reviewed: 09 Jul 2002
Birmingham - Birmingham MND Care and Research Centre Queen Elizabeth Hospital University Hospitals Birmingham NHS Trust Edgbaston, Birmingham B15 2TH Phone: +44-121-472 1311 ext 8626 Fax: +44-121-414 4509 E-mail: Medical Director: Prof. KE Morrison, Dr. HS Pall Speciality: Sporadic and familial MND Other medical specialties: Respiratory physician, gastroenterologist, neurophysiologists, physical therapists, occupational therapists, speech and language therapists, dietetics Other diseases treated: Spinal muscular atrophy, other motor neurone disorders, neuromuscular diseases Other information: Collaborator in European Familial ALS study group; member of the European ALS Consortium	Research emphasis: Molecular genetic and cellular studies of familial and sporadic MND; clinical trials Clinical trials in progress: Currently participating in the ExonHit trial and recruiting to the ONO study. Contact: Prof. KE Morrison Phone: +44-121-414-4507 Fax: +44-121-414-4509 E-mail: Record last reviewed: 23 Jan 2007